The advanced economies are continuously pursuing economic restructuring, moving further from manufacturing and services towards the creative sectors with high value added, and the more recent economic recessions and crises seem to speed up such a trend. However, according to specialists, creativity itself does not act and does not sustain on its own, but needs to be cultivated (Mokyr J., 1990). It has to be constantly encouraged and reproduced within the companies, at local/regional level and in the entire society, especially in circumstances of a continuously changing environment where all the economies have to coexist and develop. A key role in this respect has the creative class and, especially, the “creative professionals”, who work in a series of knowledge-intensive industries. The involvement of universities in order to ensure labor penetration on the creative job market requires from their part to promote innovative educational methods, in the sense of merging the business education with the creative education. Investing in R&D, enforcing adequate educational policies, ensuring collaboration between universities and business companies in both drawing up curricula and adequately integrating the creative professionals in the labor market are but a few of the priorities of a modern society. The main research question of our paper5 is focused on the dynamics of creative industries in Romania and on the possibilities of interconnection between the economic agents and academia in order to promote networks in the creative and cultural industries. In this respect, based on the method of creative industries mapping and on domestic and international economic and business statistics, the paper attempts a first analysis of the share, development and spread of creative sectors in the national economy and, especially, in the regional economies. Though the results reveal certain positive trends regarding the development of creative sectors at national and regional level, there are also signs of stagnation or volatility of activity, and of high concentration in certain regional centers and low spillover power of the current creative networks and clusters. Thus, eventual unreasonably high policy expectations must be adjusted to the Romanian realities, requiring, among others, a realistic approach regarding the evolution of the creative workforce and the need of functional connections of the creative and cultural activities within and outside their local headquarters.